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Computed Tomography versus Sleep Endoscopy (DISE) to Predict the Effectiveness of Mandibular Advancement Devices in Adult Patients with Obstructive Sleep Apnea: A Protocol for Systematic Review

datacite.subject.fosCiências Médicas::Medicina Básica
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg04:Educação de Qualidade
datacite.subject.sdg17:Parcerias para a Implementação dos Objetivos
dc.contributor.authorCebola, Pedro
dc.contributor.authorCaroça, Cristina
dc.contributor.authorDonato, Helena
dc.contributor.authorCampos, Ana
dc.contributor.authorDias, Sara Simões
dc.contributor.authorPaço, João
dc.contributor.authorManso, Cristina
dc.date.accessioned2026-10-21T13:35:02Z
dc.date.available2026-10-21T13:35:02Z
dc.date.issued2023-10-01
dc.description.abstractObstructive sleep apnea is a sleep disorder with a high prevalence in the world population. The mandibular advancement device is one of the options for treating obstructive sleep apnea. Neck computed tomography and drug-induced sleep endoscopy are complementary diagnostic tests that may help predict the effectiveness of mandibular advancement devices. This study aims to analyze the best method for predicting the effectiveness of mandibular advancement devices in the therapeutic approach to obstructive sleep apnea. PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science Core Collection databases will be comprehensively searched. We will include randomized clinical trials, non-randomized prospective or retrospective clinical studies, case controls, cohort studies, and case series. Two authors will independently conduct data extraction and assess the literature quality of the studies. The analysis of the included literature will be conducted by Revman 5.3 software. The outcomes that will be analyzed are craniofacial characteristics, cephalometric assessments, site and type of obstruction of the upper airway, mean values of the apnea–hypopnea index, and SaO2 verified in the initial and follow-up polysomnography. This study will provide reliable, evidence-based support for the clinical application of mandibular advancement devices for obstructive sleep apnea.eng
dc.description.sponsorshipThis work is financed by national funds through the FCT-Foundation for Science and Technology, I.P., under the project UIDB/04585/2020.
dc.identifier.citationCebola, P.; Caroça, C.; Donato, H.; Campos, A.; Dias, S.S.; Paço, J.; Manso, C. Computed Tomography versus Sleep Endoscopy (DISE) to Predict the Effectiveness of Mandibular Advancement Devices in Adult Patients with Obstructive Sleep Apnea: A Protocol for Systematic Review. J. Clin. Med. 2023, 12, 6328. https://doi.org/10.3390/ jcm12196328.
dc.identifier.doi10.3390/jcm12196328
dc.identifier.eissn2077-0383
dc.identifier.urihttp://hdl.handle.net/10400.8/17101
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relationEgas Moniz Interdisciplinary Research Center
dc.relation.hasversionhttps://www.mdpi.com/2077-0383/12/19/6328
dc.relation.ispartofJournal of Clinical Medicine
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectsleep apnea
dc.subjectoral appliance
dc.subjectcomputed tomography
dc.subjectsleep endoscopy
dc.titleComputed Tomography versus Sleep Endoscopy (DISE) to Predict the Effectiveness of Mandibular Advancement Devices in Adult Patients with Obstructive Sleep Apnea: A Protocol for Systematic Revieweng
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDB/04585/2020
oaire.awardTitleEgas Moniz Interdisciplinary Research Center
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04585%2F2020/PT
oaire.citation.endPage10
oaire.citation.issue19
oaire.citation.startPage1
oaire.citation.titleJournal of Clinical Medicine
oaire.citation.volume12
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameDias
person.givenNameSara
person.identifier.ciencia-idAA1F-9375-B5E6
person.identifier.orcid0000-0001-6782-7481
person.identifier.ridI-9965-2018
person.identifier.scopus-author-id33367487300
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublicationa49e0bc6-cfea-4033-aebf-a1ef9e4c5e7b
relation.isAuthorOfPublication.latestForDiscoverya49e0bc6-cfea-4033-aebf-a1ef9e4c5e7b
relation.isProjectOfPublication46e0b956-2720-4897-b94e-2cf79b9095ac
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Obstructive sleep apnea is a sleep disorder with a high prevalence in the world population. The mandibular advancement device is one of the options for treating obstructive sleep apnea. Neck computed tomography and drug-induced sleep endoscopy are complementary diagnostic tests that may help predict the effectiveness of mandibular advancement devices. This study aims to analyze the best method for predicting the effectiveness of mandibular advancement devices in the therapeutic approach to obstructive sleep apnea. PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science Core Collection databases will be comprehensively searched. We will include randomized clinical trials, non-randomized prospective or retrospective clinical studies, case controls, cohort studies, and case series. Two authors will independently conduct data extraction and assess the literature quality of the studies. The analysis of the included literature will be conducted by Revman 5.3 software. The outcomes that will be analyzed are craniofacial characteristics, cephalometric assessments, site and type of obstruction of the upper airway, mean values of the apnea–hypopnea index, and SaO2 verified in the initial and follow-up polysomnography. This study will provide reliable, evidence-based support for the clinical application of mandibular advancement devices for obstructive sleep apnea.
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